Mei-Yu Hsu, MD, PhD
2010–present Clinical Assistant Professor of Dermatology, Tufts University
2006–2010 Assistant Professor of Pathology, Harvard Medical School
2006–2010 Associate Pathologist, Brigham and Women’s Hospital
2006–2010 Consultant Pathologist, Dana-Farber Cancer Institute
2005–2006 Assistant Professor, Molecular Biology Graduate Program,
University of Iowa
2003–2006 Assistant Professor of Pathology & Dermatology, University of Iowa
2002–2003 Fellow, Dermatopathology, UT Southwestern Medical Center
1998–2003 Visiting Scientist—Tumor Biology, Wistar Institute
1998–2002 Resident, Pathology, Thomas Jefferson University Hospital
1997–1998 Fellow, Tumor Biology, Wistar Institute
1991–1992 Rotating Intern, Chung-Ho Memorial Hospital
1997 PhD, University of Pennsylvania
1992 MD, Kaohsiung Medical University
2003 Dermatopathology (American Boards of Pathology and Dermatology)
2002 Anatomic and Clinical Pathology (American Board of Pathology)
1996 Standard ECFMG
International Federation of Pigment Cell Societies
PanAmerican Society for Pigment Cell Research
College of American Pathologists (Fellow and Inspector)
Melanoma Research Foundation
Society for Melanoma Research (Member)
American Society of Dermatopathology (Fellow)
International Association of Chinese Pathologists
Society for Investigative Dermatology
Dana-Farber/Harvard Cancer Center
American Association for Cancer Research
Hsu MY, Yang MH, Schnegg CI, Hwang S, Ryu B, Alani RM. Notch3 signaling-mediated
melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis
and niche morphogenesis. Lab Invest. 2017 Jun; 97(6):725–736.
Schnegg CI, Yang MH, Ghosh SK, Hsu MY. Induction of Vasculogenic Mimicry
Overrides VEGF-A Silencing and Enriches Stem-like Cancer Cells in Melanoma.
Cancer Res. 2015 Apr 15; 75(8):1682–90.
Mak AB, Schnegg C, Lai C-Y, Yang MH, Ghosh S, Moffat J, HsuM-Y. CD133-targeted
niche-dependent therapy in cancer: A multi-pronged approach. Am J Pathol.
Pinc A, Somasundaram R, Wagner C, Hormann M, Karanikas G, Jalili A, Bauer
W, Brunner P, Grabmeier-Pfistershammer K, Gschaider M, Lai, C, Hsu M-Y,
Herlyn M, Sting G, Wagner S. Targeting CD20 in melanoma patients at high
risk of disease recurrence. Mol Ther. 2012; 20:1056–1062.
Lai C-Y, Schwartz BE, Hsu M-Y. CD133+ melanoma subpopulations contribute
to perivascular niche morphogenesis and tumorigenicity through vasculogenic
mimicry. Cancer Res. 2012; 72(19):5111–5118.
De Luca A, Laumura L, Strizzi L, Roma C, Antonio AD, Margaryan N, Pirozzi
G, Hsu M-Y, Botti G, Mari E, Hendrix MJC, Salomon DS, Normanno N. Expression
and functional role of CRIPTO-1 in cutaneous melanoma. Br J Cancer. 2011;
Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA. Differentiation
of zebrafish melanophores depends on transcription factors AP2 alpha and
AP2 epsilon. PLoS Genet. 2010 Sep 16; 6(9):e1001122.
McAllister JC, Zhan Q, Weishaupt C, Hsu MY, Murphy GF. The embryonic morphogen,
Nodal, is associated with channel-like structures in human malignant melanoma
J Cutan Pathol. 2010 Apr; 37 Suppl 1:19–25.
Laga AC, Lai C-Y, Zhan Q, Huang SJ, Velazquez EF, Yang Q, Hsu M-Y, Murphy
GF. Expression of the embryonic stem cell transcription factor SOX2 in
human skin: relevance to melanocyte and Merkel cell biology. Am J Pathol.
Martin, JE, Hsu M-Y, Wang LC. A unique clinical presentation of multiple
tumors of the follicular infundibulum. J Am Acad Dermatol. 2009; 60:885–886.
Menke J, Hsu M-Y, Byrne KT, Lucas JA, Rabacal WA, Croker BP, Zong X-H,
Stanley ER, Kelley VR. Sunlight triggers cutaneous lupus through a colony
stimulating factor-1 (CSF-1) dependent mechanism in MRL-Faslpr mice. J
Immunol. 2008; 181:7367–7379.
Hsu M-Y, Rovinsky S, Lai CY, Qasem S, Liu X, How J, Engelhardt JF, Murphy
GF. Aggressive melanoma cells escape from BMP7-mediated autocrine growth
inhibition through coordinated Noggin upregulation. Lab Invest. 2008;
88:842–855. (Editorial highlight in: Lab Invest 2008; 88:795).
McNeill MS, Paulsen J, Bonde G, Burnight E, Hsu, M-Y, Cornell RA. Cell
death of melanophores in zebrafish trmp7 mutant embryos depends on melanin
synthesis. J Invest Dermatol. 2007; 127:2020–2030.