InformTx™ Therapeutic Drug Monitoring
Make Evidence-Based Treatment Decisions
Use InformTx therapeutic drug monitoring (TDM) assays are available for
eight biologic drugs used to treat for patients with inflammatory bowel
- Remicade® (infliximab)
- Humira® (adalimumab)
- Cimzia® (certolizumab pegol)
- Entyvio® (vedolizumab)
- Stelara® (ustekinumab)
- Simponi® (golimumab)
- Inflectra® (infliximab-dyyb)
- Renflexis® (infliximab-abda)
What Is InformTx?
InformTx therapeutic drug monitoring (TDM) assays measure both drug and
anti-drug antibody levels in a patient’s blood.
InformTx testing uses laboratory-validated ELISA technology. Unique for
TDM in the United States, the InformTx report gives you easy-to-interpret results:
- Quantitative test results
- Historical test result data
- Guidance for results
InformTx TDM requires five to seven milliliters of peripheral blood in
a serum separator tube, and the results are reported within five days.
What is Therapeutic Drug Monitoring? Why Order TDM?
InformTx helps you maximize the efficacy of biologic therapy. Use for all
of your IBD patients—whenever you need therapeutic guidance.
IDM allows you to:
Optimize at induction to ensure therapeutic drug levels
Monitor during maintenance to track drug and anti-drug antibody (ADAb) levels
Manage at loss of response/no response to identify reason
Many factors influence individual patient response to biologic therapy:
- Systemic inflammation
- Other drug therapies
- Pharmacogenetic factors
- Disease phenotype
- Body mass
- Presence of anti-drug antibodies
Individual response to biologic drugs varies greatly. Variability by patients
leads to four patient types: responders, initial responders, partial responders,
and non-responders. InformTx enables clinicians to manage all patient types.
Ready to Order InformTx Testing?
InformTx testing can be ordered by physicians and other clinicians. Patients
who are interested in InformTx therapeutic drug monitoring should contact
their healthcare providers to discuss if TDM is right for them.
Clinicians should contact a Inform Diagnostics Client Advocate to order
InformTx requisitions and collection kits, at no cost to your practice.
Questions? Contact our client services team or your Inform Diagnostics sales representative to learn more about our pathology