InformTx™ Therapeutic Drug Monitoring

Make Evidence-Based Treatment Decisions

InformTx therapeutic drug monitoring (TDM) assays are available for eight biologic drugs used to treat patients with inflammatory bowel disease (IBD):

  • Remicade® (infliximab)
  • Humira® (adalimumab)
  • Cimzia® (certolizumab pegol)
  • Entyvio® (vedolizumab)
  • Stelara® (ustekinumab)
  • Simponi® (golimumab)
  • Inflectra® (infliximab-dyyb)
  • Renflexis® (infliximab-abda)

How does InformTx therapeutic drug monitoring work?

InformTx testing uses laboratory-validated ELISA technology. Unique for TDM in the United States, the InformTx report gives healthcare providers easy-to-interpret results:

InformTx TDM requires five to seven milliliters of peripheral blood in a serum separator tube, and the results are reported within five business days. Healthcare providers should contact Inform Diagnostics to request collection kits and supplies. Patients should ask their healthcare provider about therapeutic drug monitoring.

What is Therapeutic Drug Monitoring? Why Order TDM?

InformTx helps healthcare providers maximize the efficacy of biologic therapy. Use for all of your IBD patients—whenever you need therapeutic guidance.

TDM enables you to:

  • Optimize at induction to ensure therapeutic drug levels
  • Monitor during maintenance to track drug and anti-drug antibody (ADAb) levels
  • Manage at loss of response/no response to identify reason

Many factors influence individual patient response to biologic therapy:

  • Systemic inflammation
  • Other drug therapies
  • Pharmacogenetic factors
  • Disease phenotype
  • Body mass
  • Immunogenicity
  • Immunomodulators
  • Presence of anti-drug antibodies

Individual response to biologic drugs varies greatly. Variability by patients leads to four patient types: responders, initial responders, partial responders, and non-responders. InformTx enables clinicians to manage all patient types.

Ready to Order InformTx Testing?

InformTx testing can be ordered by physicians and other clinicians. Patients who are interested in InformTx therapeutic drug monitoring should contact their healthcare providers to discuss if TDM is right for them.

Clinicians should contact an Inform Diagnostics Client Advocate to order InformTx requisitions and collection kits, at no cost to your practice.

  • Phone 844.305.2166
  • Fax 866.688.3280

Questions? Contact our client services team or your Inform Diagnostics sales representative to learn more about our pathology laboratory services.