IRVING, Texas, March 28, 2017 — Inform Diagnostics, the largest U.S. independent
anatomic pathology laboratory, continues to expand its
InformTx™ therapeutic drug monitoring (TDM) capabilities, now testing for Simponi (golimumab) as well as patient-developed
antibodies to Simponi. This is the first TDM assay available in the United
States for Simponi. With this addition, Inform Diagnostics now performs
TDM for six biologic drugs that treat inflammatory bowel disease (IBD).
InformTx also is the only TDM (with anti-drug antibodies) available in
the United States for Cimzia® (certolizumab pegol) and Stelara®
(ustekinumab). The company also continues to offer TDM for Remicade®
(infliximab), Humira® (adalimumab), and Entyvio® (vedolizumab).
The InformTx report is unique in that it provides clinicians with quantitative
test results, historical test result data, and
guidance from the most up-to-date peer-reviewed scientific literature. Inform Diagnostics Life
Sciences uses laboratory-validated ELISA technology for InformTx TDM,
and testing results are reported within five days.
“Monitoring of therapeutic drug levels and anti-drug antibodies is
extremely important for the effective management of inflammatory bowel
Richard Lash, MD, Chief Medical Officer and Executive Vice President of Operations for
Inform Diagnostics. “With our InformTx offering now encompassing
six drugs, Inform Diagnostics can serve even more gastroenterologists
and their patients.”
Why Therapeutic Drug Monitoring?
Therapeutic drug monitoring is utilized by physicians to monitor an individual’s
response to biologic drugs, as they vary greatly from patient to patient.
Factors influencing individual patient response to biologic therapy include
systemic inflammation, other drug therapies, pharmacogenetic factors,
disease phenotype, body mass, immunogenicity, immunomodulators, and the
presence of anti-drug antibodies. Variability by patients leads to four
patient types: responders, initial responders, partial responders, and
non-responders. InformTx enables clinicians to manage all patient types,
and is now capable of evaluating six different biologic drugs used to
About Inform Diagnostics
Inform Diagnostics provides proven high-quality anatomic and clinical
pathology services, focusing on the fields of gastroenterology, dermatology,
hematology, urology, and breast health. The company’s team of more
than 80 distinguished subspecialist pathologists utilizes state-of-the-art
laboratories to serve more than 5,500 patients every day. Inform Diagnostics Life
Sciences’ difference is based on consensus-based medicine (including
comprehensive sub-subspecialization, unified terminology and criteria,
daily consensus conferences, and extensive educational activities), rigorous
quality assurance, active clinical research, innovation in testing, technological
advancements, and health IT consulting services for clinician clients.
Headquartered in Irving, Texas, Inform Diagnostics is a subsidiary of
Inform Diagnostics Holdings Inc., one of Japan’s largest clinical diagnostics
and laboratory testing service providers. For more information, visit
Simponi, Stelara and Remicade are registered trademarks of Janssen Biotech,
Inc. Humira is a registered trademark of AbbVie Inc. Cimzia is a registered
trademark of UCB. Entyvio is a registered trademark of Millennium Pharmaceuticals Inc.
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