Lynch Syndrome research presented at DDW 2011 by Mark Redston, MD and Richard
Lash, MD, found that the prevalence of LS among patients with newly diagnosed
HGD adenomas in the community practice setting is similar to CRC patients
in the same population (3.0% vs. 3.6%). In addition, the prevalence of
LS is highest in HGD adenoma patients under age 50, however, more than
50% are older than age 50. Almost 50% of newly diagnosed HGD adenoma patients
with probable LS do not meet family or personal history criteria for HNPCC.
These results suggest there is value to routinely screen for LS in patients
with HGD adenomas and provide a novel approach for detection of LS prior
to the development of cancer.
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