Rectal carcinoid tumors are rare (0.05% in the general population, SEER
data) and are usually discovered incidentally in routine colonoscopy biopsies.
Although immunohistochemistry with neuroendocrine markers synaptophysin
and/or chromogranin is often used to confirm the diagnosis, its utility
is not well established. The aims of this study were to (1) determine
the prevalence of rectal carcinoid tumors in a large cohort of US outpatient
colonoscopy patients and (2) evaluate whether the routine use of immunohistochemical
stains is necessary for a definitive diagnosis.
To read the rest of this article, please contact