Blog Posts in 2012

A subset of patients undergo both EGD and colonoscopy on the same day (bidirectional endoscopy or BDE). Although no clear guidelines exist, same-day bidirectional endoscopy has been recommended for patients with anemia or positive fecal occult blood test (FOBT). In a recent study (Urquhart et al, ...

Physiologic decline occurs in the stomach of every aging human, but pathologic conditions are affected by genetic and environmental factors. Worldwide, the most important of these is believed to be H. pylori -gastritis and its sequelae. However, in the past several decades most industrialized ...

The cecal patch is defined as the discontinuous involvement of the cecum in patients with otherwise left-sided ulcerative colitis (UC); see Figures 1 and 2. Several studies have failed to show consistent clinical differences between UC patients with and without a cecal patch. Also, the reported ...

First described by Jules Haot in 1988, lymphocytic gastritis (LG) was initially believed to correspond to an entity mentioned in 1945 by the Belgian gastroenterologist François Moutier, who reported a nodular form of gastritis characterized by centrally eroded or ulcerated depressions picturesquely ...

While Inform Diagnostics is recognized as a leading provider of academic-caliber GI pathology diagnostic services, did you know about our expertise in hepatopathology? Several pathologists at Inform Diagnostics have extensive experience and expertise in hepatopathology, including medical liver ...

Colorectal cancer (CRC) occurring in the setting of Inflammatory Bowel Disease (IBD) is relatively uncommon. Mutations in p53 have been found in these cancers, and have been proposed as a possible genetic marker with utility in detection of these cancers and their precursor dysplasias. We undertook ...

Non-steroidal anti-inflammatory drugs (NSAIDs) are a significant cause of morbidity and mortality. In the upper gastrointestinal (GI) tract, NSAIDs are known to cause ulcers/erosions and even perforation. Lower GI tract injury, especially of the right colon, has been described more recently, ...

Reactive gastropathy is a histopathologic term widely understood by gastroenterologists as an indication of gastric damage associated with either bile reflux or chronic NSAID use. The epidemiology of reactive gastropathy and its relationship with other conditions of the gastrointestinal tract ...

An Emerging Ancillary Technique in Risk Stratification The diagnosis of dysplasia in the setting of Barrett’s esophagus is one of the most challenging areas of GI pathology and is associated with high levels of inter-observer variability amongst general pathologists. In one recent study, 85% ...

Another Major Presence for Inform Diagnostics Washington, D.C. - For the past four years, the conspicuous presence of researchers from Inform Diagnostics has become a tradition at the annual meeting of the American College of Gastroenterology. This year was no exception: Fifteen abstracts were ...