Atrophic autoimmune gastritis (AIG) is uncommon and most series include
few patients. An accurate diagnosis rests on adequate gastric biopsy sampling
(rarely done); thus, controls have often been subjects in whom AIG was
excluded based on insufficient sampling.
H. pylori infection was unrecognized until 1985–1990, and most studies on
AIG have been carried out before that time. Therefore, they may include
large numbers of patients with
H. pylori gastritis.
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