National differences in the prevalence of eosinophilic esophagitis (EoE)
have been described, but it is not clear whether these differences are
real (due to differences in genetic or environmental factors) or spurious
(due to national differences in awareness of the condition among physicians
and in their recognition of the endoscopic and histological features of EoE).
Prevalence rates for EoE in reports from Asia have been highly variable
(e.g., 0.01% in a study from Japan, 0.34% in a study from China, 6.6%
in a study from Korea).
To minimize confounding due to national differences in physician factors
relating to the diagnosis of EoE, we estimated the prevalence of EoE in
patients of different ethnicities who had endoscopy performed in the United
States with esophageal biopsies evaluated by a group of gastrointestinal
pathologists in the United States.
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