PTEN (phosphatase and tensing homolog) on chromosome 10q23 is a key tumor
suppressor gene that is deleted or inactivated in 30-40% of clinically
localized prostate cancers (PCa) and is frequently associated with high risk PCa.
Loss of PTEN tumor suppressor gene is increasingly being analyzed on prostate
core biopsies (NBXs) due to its prognostic relevance in cancer (PCa) risk
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