Blog Posts in December 2015
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Low prevalence of Helicobacter pylori infection among patients with inflammatory bowel disease
There is some preliminary evidence to suggest that patients with inflammatory bowel disease (IBD) are less frequently infected with Helicobacter pylori than the general population.
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Carcinoma of the Collecting Ducts of Bellini and Renal Medullary Carcinoma: Clinicopathologic Analysis of 52 Cases of Rare Aggressive Subtypes of Renal Cell Carcinoma With a Focus on Their Interrelationship
Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma are rare aggressive renal tumors. First described in 1949, case reports and review articles constitute a major source of information on collecting duct carcinoma, whereas Davis and colleagues and the pediatric tumor registry ...
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Helicobacter pylori is a Risk Factor for Colonic Neoplasms
Previous publications relying mostly on small case-control studies have suggested that infection with H. pylori confers a 1.4 – 1.6 fold increased risk for colonic adenoma or colon cancer.
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Gastric heterotopia in the proximal oesophagus ("inlet patch"): Association with adenocarcinomas arising in Barrett mucosa
The prevalence of inlet patches and their association with other conditions of the gastrointestinal tract had been studied prospectively in small series from tertiary care facilities; little is known about practice patterns in private outpatient clinics and endoscopy centers.
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Predictive Value of ERG Oncoprotein Expression and Pathologic Parameters In the Stratification of Prostate Cancer Risk Associated With High Grade Prostatic Intraepithelial Neoplasia (HGPIN) Diagnosis In Prostate Needle Biopsy
This research was presented at the AUA annual conference in May 2015, in New Orleans. High-grade prostatic intraepithelial neoplasia (HGPIN) is a putative neoplastic precursor lesion of prostate cancer (PCa). Historically, HGPIN in needle biopsy has been associated with high predictability of ...
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PTEN Protein Loss and Genomic Deletions in Prostate Cancer: A Comparative Study of Immunohistochemistry and Four-Color FISH Assay
PTEN (phosphatase and tensing homolog) on chromosome 10q23 is a key tumor suppressor gene that is deleted or inactivated in 30-40% of clinically localized prostate cancers (PCa) and is frequently associated with high risk PCa. Loss of PTEN tumor suppressor gene is increasingly being analyzed on ...
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Signet Ring Cell Carcinoma of the Esophagus
Signet ring cell carcinoma is a histologic variant of adenocarcinoma characterized by a population of loose tumor cells whose cytoplasm appears almost entirely occupied by mucin. In rare instances, signet ring cell carcinoma occurs at the gastroesophageal junction without association to any such ...
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Demographic and Socio-economic Influences on H. pylori-induced Changes to the Gastric Mucosa
Over a lifetime, gastric infection with Helicobacter pylori (Hp) can lead to chronic active gastritis (CAG), chronic inactive gastritis (CIG), intestinal metaplasia (IM) and atrophy (ATR). Little is known whether such changes occur similarly among different ethnic groups and how they are affected by ...
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