Evan S. Dellon, Anne F. Peery, Nicholas J. Shaheen, Douglas R. Morgan,
Jennifer M. Hurrell, Richard H. Lash, Robert M. Genta
Published in
Gastroenterology, 2011.
Eosinophilic esophagitis (EoE) is of increasing prevalence and believed
to result from allergic processes. Helicobacter pylori has been inversely
associated with allergic diseases, but there is no known relationship
between H pylori, EoE, and esophageal eosinophilia. We investigated the
association between esophageal eosinophilia and H pylori infection.
Methods:
We performed a crosssectional study of data, collected from a US pathology
database, on 165,017 patients in the United States who underwent esophageal
and gastric biopsies from 2008 through 2010. Patients with and without
H pylori on gastric biopsy were compared, and odds of esophageal eosinophilia were
determined.
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