East Asian countries have historically reported low incidences of microscopic
colitis and inflammatory bowel disease (1); however, it is unclear whether
these data reflect genetic or environmental factors or are the result
of different diagnostic criteria among physicians and pathologists.
This question could be answered, at least in part, by comparing the prevalence
of microscopic colitis (lymphocytic and collagenous) and IBD (ulcerative
colitis, UC, and Crohn disease, CD) in patients of East Asian ancestry
who live in the United States and have had colonoscopies in the United
States to a group of non-Asian U.S. patients.
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