L. Dean, L. White, E. Hayes, K. Webber, T. Zeliadt, E. Kroman, W. L. Flejter, PhD – Inform Diagnostics, AZ […]
Abstract Category: Hematology
A Rare (11;22)(q23;q11.2) Translocation in a Patient with Chronic Lymphocytic Leukemia
K. Horvath, K. Webber, E. Hayes, T. Zeliadt, W.L. Flejter PhD – Inform Diagnostics Life Sciences, Phoenix, AZ We received […]
Plasma Cell Enrichment: A Valuable Tool to Increase Abnormality Detection Rates in Plasma Cell Disorders by FISH
E. Kroman, L. Scott, Q. Zhao, J. Zhang, T. Golding, M.L. Miller, W.L. Flejter – Inform Diagnostics Cytogenetic analysis of […]
Multicolor Flow Cytometry Detects Monoclonal Plasma Cells in the Vast Majority of Patients with Plasma Cell Disorders Shown to Have Genetic Abnormalities by Fluorescence In Situ Hybridization (FISH)
Raul Braylan, Karina Baggiani, Tiana Golding, Eric Kroman, Michael L. Miller, and Wendy L. Flejter The flow cytometric analysis is […]
The Importance of Lymphoid Stimulation and FISH to Detect Complex Translocations in Oncology
K. Stiner, N. Lee, K. Abdi, L. White, L. Dean, Q. Virgo, W.L. Flejter PhD A bone marrow sample was […]
What to do about: Low level monoclonal B-lymphocyte populations
In recent years, flow cytometric analysis of the blood and bone marrow has become a standard of practice for the […]
Getting to the point: Somatic point mutations influence the clinical features and survival in myelodysplastic syndromes
According to the National Institutes of Health, the frequency and incidence of myelodysplastic syndromes (MDS) is increasing in the US […]
Paroxysmal Nocturnal Hemoglobinuria (PNH): A Life Threatening Disease Caused by Unregulated Complement Activation
In clinical terms, paroxysmal nocturnal hemoglobinuria (PNH) is synonymous with glycosylphosphatidylinositol (GPI) deficiency, and is an acquired clonal disorder associated […]
The Role of Flow Cytometry in the Diagnosis of PNH
Screening and diagnosis of patients with PNH has improved with the development of flow cytometry.1 Immunophenotypic analysis of GPI-linked antigen […]
Plasma Cell Enrichment: Increasing the Detection Rate of Plasma Cell Disorders
Plasma cell enrichment techniques concentrate the overall population of plasma cells, thereby increasing the detection and frequency of abnormalities. Cytogenetic […]
