Expert Pathologists

Alejandro Peralta Soler, MD, PhD

Academic Appointments

2005–2006 Assistant Professor of Pathology, Duke University Medical Center

Postdoctoral Training

2004–2005 Fellow, Dermatopathology, Cornell Medical College

2001–2004 Resident, Anatomic Pathology, State University of New York, Downstate Health Science Center (Chief of Residents 2003–2004)

1980–1983 Resident, Anatomic Pathology, National University of Cordoba, Argentina


1986 PhD, Electron Microscopy Center, National University of Cordoba School of Medicine, Argentina

1979 MD, National University of Cordoba School of Medicine, Argentina


2005 Dermatopathology

2004 Anatomic Pathology

Professional Societies

American Society of Clinical Pathology

American Society of Dermatopathology

Cincinnati Dermatology Society

Select Publications

Smith C, Chang MY, Parker KH, Beury DW, DuHadaway JB, Flick HE, Boulden J, Sutanto-Ward E, Peralta Soler A, Laury-Kleintop LD, Mandik-Nayak L, Metz R, Ostrand-Rosenberg S, Prendergast GC, Muller AJ. (2012) IDO is a nodal pathogenic driver of lung cancer and metastasis development. Cancer Discov. 2(8):722–35.

Chang MY, Boulden J, Valenzano MC, Peralta Soler A, Muller AJ, Mullin JM, Prendergast GC. (2012) Bin1 attenuation suppresses experimental colitis by enforcing intestinal barrier function. Dig Dis Sci. 57(7): 1813–21.

Chang MY, Smith C, DuHadaway JB, Pyle JR, Boulden J, Peralta Soler A, Muller AJ, Laury-Kleintop LD, Prendergast GC. (2011) Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase. Cancer Biol Ther. 12(12):1050–8.

Ramalingam A, Wang X, Gabello M, Valenzano MC, Peralta Soler A, Ko A, Morin PJ, Mullin JM. (2010) Dietary methionine restriction improves colon tight junction barrier function and alters claudin expression pattern. Am J Physiol Cell Physiol. 99(5): C1028–35.

Muller AJ, DuHadaway JB, Chang MY, Ramalingam A, Sutanto-Ward E, Boulden J, Peralta Soler A, Mandik-Nayak L, Gilmour SK, Prendergast GC. (2010) Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion. Cancer Immunol Immunother. 59(11): 1655–63.

Muller AJ, Sharma MD, Chandler PR, DuHadaway JB, Everhart ME, Johnson BA, Kahler DJ, Pihkala J, Peralta Soler A, Munn DH, Prendergast GC, Mellor AL (2008) Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing 2,3 dioxygenase. Proc Natl Acad Sci USA. 105: 17073–8.

Walters RW, Peralta Soler A, Selim MA (2009) Kaposi’s sarcoma presenting as yellowish-green penile plaques in a black man with HIV. Cutis. 88(1): 14–6.

Burchette JL, Pham TT, Higgins SP, Cook JL, Peralta Soler A. (2008) Expression of cadherin/catenin cell-cell adhesion molecules in a onychomatricoma. Int J Sug Pathol. 16:349–53.

Ramalingam A, Duhadaway JB, Sutanto-Ward E, Wang Y, Dinchuk J, Huang JM, Donover PS, Boulden J, McNally LM, Peralta Soler A, Muller AJ, Duncan MK, Prendergast GC (2008) Bin3 ablation causes ocular cataracts and increases the incidence of lymphomas and solid tumors during aging. Cancer Res. 68:1683–90.

Peralta Soler A, Burchette JL, Bellet JS, Olson JA Jr (2007). Cell adhesion protein expression in melanocytic matricoma. J Cut Pathol. 34: 456–60.

Waugh MS, Peralta Soler A, Robboy SJ (2007) Silent corticotroph cell pituitary adenoma in a stroma ovarii. Int J Gynecol Pathol. 26:26–9.

Ghaneie A, Zemba-Palko V, Itoh H, Itoh K, Sakamuro D, Nakamura S, Peralta Soler A, Prendergast GC (2007) Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival. Cancer Biol. Ther. 62: 192–4.

Chang M-Y, Boulden J, Ghaneie A, Sutanto-Ward E, Duhadaway JB, Zemba-Palca V, Ito H, Itoh K, Sakamuro D, Nakamuro S, Peralta Soler A, Muller AJ, Prendergast GC (2007) Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression. Cancer Res. 67: 100–7.

Gutierrez S, Mukdsi JH, Aoki A, Torres AI, Peralta Soler A, Orgnero EM (2007) Ultrastructural immunolocalization of IGF-1 and insulin receptors in rat pituitary culture: evidence of a functional interaction between gonadotroph and lactotroph cells. Cell Tissue Res. 327:121–32.

Gallego Attis M, Burchette JL, Selim MA, Pham T, Peralta Soler A (2006) Differential expression of N-cadherin distinguishes a subset of metastasizing desmoplastic melanomas. Hum Pathol. 37: 899–905.

Peralta Soler A, Soler de Peralta J (2005) The confabulatory semiotics: Naming and cognition of diseases by pathologists. Med Health Care and Phil. 8:351–5.