Expert Pathologists

Chandrika Sreekantaiah, PhD

Director, Cytogenetics/FISH 

Academic Appointments

2009–2014 Chief, Cytogenetics, Division of Cytogenetics and Molecular Pathology, North Shore University Hospital and Long Island Jewish Medical Center, NY

2009–2014 Assistant Professor of Pathology, Hofstra North Shore-LIJ School of Medicine, NY

1994–2001 Chief, Division of Clinical and Cancer Cytogenetics, New York Medical College – University Pathology, NY

1994–2001 Assistant Professor, Department of Pathology, New York Medical College, NY

1990–1994 Associate Professor of Cytogenetics, Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India

Postdoctoral Training

1991–1993 Research Associate, Laboratory of Cancer Genetics and Cytogenetics, Memorial Sloan-Kettering Cancer Center, New York, NY

1988–1990 Research Associate, The Genetics Center and Cancer Center Southwest Biomedical Research Institute, Scottsdale, AZ

1986–1988 Research Affiliate, Roswell Park Memorial Institute, Buffalo, NY

1985–1986 Research Associate, Kidwai Memorial Institute of Oncology, Bangalore, India

Education

1985 Ph.D. Zoology (Cancer Cytogenetics), Bangalore University

Certifications

American Board of Medical Genetics and Genomics, Clinical Cytogenetics        

Professional Societies

American Board of Medical Genetics

American College of Medical Genetics– Fellow 

American Society of Hematology

American Society of Human Genetics 

Cancer Genomics Consortium

Peer-Reviewed Articles

Van Dyke DL, Werner L, Rassenti LZ, Neuberg D, Ghia E, Heerema NA, Dal Cin P, Del Aquila M, Sreekantaiah C, Greaves AW, Kipps T, Kay NE. The Dohner Fluorescence in situ Hybridization Prognostic Classification of Chronic Lymphocytic Leukemia (CLL): The CLL Research Consortium Experience. British J of Hematology 173:105-113, 2016.

Liu B, Kerath SM, Sekeres MA, Fryzek JP, Sreekantaiah C, Mason CR, Kolitz J, Taioli E. Myelodysplastic syndromes spatial clusters in disease etiology and outcome. Leukemia and Lymphoma 5:1-8, 2015.

Haghi N, Brody J, Mahmood N, Gheewala D, Allen SL, Sreekantaiah C, Zhang X. B-cell precursor acute lymphoblastic leukemia with isolated t(14;19)(q32;q13) abnormality involving CEBPG gene. Leukemia and Lymphoma 56:2978-81, 2015.

Mosquera JM, Sboner A, Zhang L, Kitabayashi N, Chen C-L, Sung YS, Wexler LH, LaQuaglia MP, Edelman M, Sreekantaiah C, Rubin MA, Antonescu CR. Recurrent NCOA2 gene rearrangements in congenital/ infantile spindle cell rhabdomyosarcoma. Genes Chromosomes Cancer 52:538-550, 2013.

Carneiro BA, Kaminer L, Eldibany M, Sreekantaiah C, Kaul K, Locker GY. Oxaliplatin-related acute myelogenous leukemia. The Oncologist 11:261-262, 2006.

Seiter K, Feldman E, Sreekantaiah C, Pozzuoli M, Weisberger J, Liu D, Papageorgio C, Weiss M, Kancherla R, Ahmed T. Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy. Leukemia 15:963-970, 2001.

Sreekantaiah C, Kronn D, Marinescu RC, Goldin B, Overhauser J. Characterization of a complex chromosomal rearrangement in a patient with a typical cat-like cry and no other clinical features of cri-du-chat syndrome. Am J Med Genet 86:264-268, 1999.

Sreekantaiah C, Rao PH, Xu L, Sacks PG, Schantz SP, Chaganti RSK. Consistent chromosomal losses in head and neck squamous cell carcinoma cell lines. Genes Chrom Cancer 11:29-39, 1994.

Rodriguez E, Sreekantaiah C, Gerald W, Reuter VE, Motzer RJ, Chaganti RSK. A recurring translocation t(11;22)(p13;q11.2) characterizes intra-abdominal desmoplastic small round-cell tumors. Cancer Genet Cytogenet 69:17-21, 1993.

Sreekantaiah C, Davis JR, Sandberg AA. Chromosomal rearrangements in leiomyosarcomas. Am J Pathol 142:293-305,1993.

Rodriguez E, Sreekantaiah C, Reuter VE, Motzer RJ, Chaganti RSK. T(12;22)(q13;q13) translocation and trisomy 8 are nonrandom aberrations in clear-cell sarcoma. Cancer Genet Cytogenet 64:107-110, 1992.

Sreekantaiah C, Appaji L, Hazarika D. Cytogenetic characterization of small round cell tumors using fine needle aspiration biopsies. J Clin Path 45:728-730,1992.

Sreekantaiah C, Karakousis CP, Leong SPL, Sandberg AA. Cytogenetic findings in liposarcoma correlate with histopathologic subtypes. Cancer 69:2484-2495, 1992.

Bridge JA, Sreekantaiah C, Mouron BSB, Neff JR, Sandberg AA, Wolman SR. Clonal chromosomal abnormalities in desmoid tumors: Implications for histopathogenesis. Cancer 69: 430-436, 1992.

Kakati S, Xiao H, Siddiqui SY, Sreekantaiah C, Weier H-UG, Green DM, Fisher JE, Allen JE. Constitutional extra chromosomal element in a family with Wilm’s tumor. Hum Genet, 87: 183-188, 1991.

Sreekantaiah C, Leong SPL, Davis JR, Sandberg AA. Intratumoral cytogenetic heterogeneity in a benign neoplasm. Cancer, 67: 3110-3116, 1991.

Kiechle-Schwarz M, Sreekantaiah C, Berger CS, Pedron S, Medchill MT, Surti U, Sandberg AA. Nonrandom cytogeneticchanges in leiomyomas of the female genitourinary tract: A report of 35 cases. Cancer Genet Cytogenet, 53: 125-136,1991.

Bridge JA, Sreekantaiah C, Neff JR, Sandberg AA. Cytogenetic findings in clear cell sarcoma of tendons and aponeuroses: Malignant melanoma of soft parts. Cancer Genet Cytogenet, 52: 101-106, 1991.

Sreekantaiah C, Karakousis CP, Leong SPL, Sandberg AA. Trisomy 8 as a nonrandom secondary change in myxoidliposarcomas. Cancer Genet Cytogenet, 51: 195-205, 1991.

Sreekantaiah C, Leong SPL, Karakousis CP, McGee DL, Rappaport C, Villar HV, Neal D, Fleming S, Wankel A, Herrington PN, Carmona R, Sandberg AA. Cytogenetic profile of 109 lipomas. Cancer Res, 51: 422-433, 1991.

Paulien S, Turc-Carel C, Dal Cin P, Sait SNJ, Sreekantaiah C, Leong SPL, Vogelstein B, Kinzler KW, Sandberg AA, Gemmil RM. Myxoid liposarcoma with t(12;16)(q13;p11) contains site-specific alterations in methylation patterns surrounding a zinc-finger protein gene that maps to the breakpoint region. Cancer Res, 50: 7902-7907, 1990.

Sreekantaiah C, Baer MR, Morgan S, Isaacs JD, Miller KB, Sandberg AA. Trisomy/Tetrasomy 13 in Acute Leukemia. Leukemia, 4:781-785, 1990.

Sreekantaiah C, Leong SPL, Sandberg AA. Complex cytogenetic changes in benign neoplasms: Report of 6 lipomas. Cancer Genet Cytogenet, 47: 113-130, 1990.

Baer MR, Sreekantaiah C, Sait SNJ, Sawyer AM, Sandberg AA, Preisler HD. Cytogenetic study of maturing granulocytes in bone marrow of patients with acute myelogenous leukemia. Leukemia, 4: 297-301, 1990.

Sreekantaiah C, Berger CS, Karakousis C, Rao U, Leong SPL, Sandberg AA. A cytogenetic subtype involvingchromosome 13 in lipoma: Report of 3 cases. Cancer Genet Cytogenet, 39: 281-288, 1989.

Sreekantaiah C, Bhargava MK, Jaya Shetty N. Chromosome 1 abnormalities in cervical carcinoma. Cancer, 62: 1317-1324, 1988.

Review Articles and Book Chapters

Sreekantaiah C, Sandberg AA. Clustering of aberrations to specific chromosome regions in benign neoplasms. Int J Cancer, 48:194-198, 1991.

Sreekantaiah C, Chaganti RSK. Cytogenetic aberrations in solid tumors. In The Cytogenetic Symposia, 1994, ACT publications, 1994.

Sreekantaiah C, Ladanyi M, Rodriguez E, Chaganti RSK. Chromosomal aberrations in soft tissue tumors: Relevance to diagnosis, classification and molecular mechanisms. Am J Pathol 144:1121-1134, 1994.

Rodriguez E, Sreekantaiah C, Chaganti RSK. Genetic changes in epithelial solid neoplasia. Cancer Res 54:3398-3406,1994.

Rodriguez E, Sreekantaiah C, Chaganti RSK. Cytogenetic and molecular studies in male germ cell tumors. In: Advancesin Genome Biology. Verma RS (ed); Vol 3: Genetics of Human Neoplasia, JAI press, Greenwich, CT. 1994.

Sreekantaiah C. The cytogenetic and molecular characterization of benign and malignant soft tissue tumors: A review. Cytogenet Cell Genet 82:13-29, 1998.

Sreekantaiah C. Cytogenetic and molecular cytogenetic aberrations in solid tumors. In The Cytogenetic Symposia Second edition, Dunn B, Mouchrani P, Keagle M (eds); AGT publications, 2005.

Sreekantaiah C. Fluorescence in situ hybridization (FISH) panels for hematological malignancies. Cytogenet Genome Res, 118: 284-296, 2007.