Expert Pathologists

Academic Appointments

2013–2019 Program Director, Urologic Pathology Fellowship, UT Southwestern Medical Center

2012–2019 Assistant Professor of Pathology and Urologic PathologistUT Southwestern Medical Center

Postdoctoral Training

2011–2012 Fellow, Urologic Pathology, University of Pittsburgh Medical Center

2010–2011 Fellow, Surgical Oncologic Pathology, Memorial Sloan Kettering Cancer Center

2006–2010 Resident, Anatomic and Clinical Pathology, New York University Langone Medical Center


2006 PhD, Temple University School of Medicine, Philadelphia

1996 MD, University of Calcutta, R G Kar Medical College, Calcutta, India


2011 Anatomic and Clinical Pathology

Professional Societies

College of American Pathologists

US and Canadian Association of Pathologists

Select Publications

Lotan Y, Boorjian SA, Zhang J, Bivalacqua TJ, Porten SP, Wheeler T, Lerner SP, Hutchinson R, Francis F, Davicioni E, Svatek RS, Chen CL, Black PC, Gibb EA. Molecular Subtyping of Clinically Localized Urothelial Carcinoma Reveals Lower Rates of Pathological Upstaging at Radical Cystectomy Among Luminal Tumors. European Urology. 2019 Aug; 76(2):200–206.

Costa DN, Goldberg K, Leon AD, Lotan Y, Xi Y, Aziz M, Freifeld Y, Margulis V, Raj G, Roehrborn CG, Hornberger B, Desai N, Bagrodia A, Francis F, Pedrosa I, Cadeddu JA. Magnetic Resonance Imaging-guided In-bore and Magnetic Resonance Imaging-transrectal Ultrasound Fusion Targeted Prostate Biopsies: An Adjusted Comparison of Clinically Significant Prostate Cancer Detection Rate. European Urology Oncology. 2019 Jul; 2(4):397–404.

Freifeld Y, Xi Y, Passoni N, Woldu S, Hornberger B, Goldberg K, Bagrodia A, Raj G, Margulis V, Cadeddu JA, Lotan Y, Francis F, Pedrosa I, G Roehrborn C, Costa DN. Optimal sampling scheme in men with abnormal multiparametric MRI undergoing MRI-TRUS fusion prostate biopsy. Urol Oncol. 2019 Jan; 37(1):57–62.

Freifeld Y, Diaz de Leon A, Xi Y, Pedrosa I, Roehrborn CG, Lotan Y, Francis F, Costa DN Diagnostic Performance of Prospectively Assigned Likert Scale Scores to Determine Extraprostatic Extension and Seminal Vesicle Invasion With Multiparametric MRI of the Prostate. AJR Am J Roentgenol. 2018 Dec 27:1–6.

Kittler R, Shiang C, Hutchinson R, Kollipara R, Kapur P, Francis F, Lotan Y. Grade progression in urothelial carcinoma can occur with high or low mutational homology: a first-step toward tumor-specific care in initial low-grade bladder cancer. Oncotarget. 2018 Jan 6; 9(10):9415–9424.

Henry G, Malewska A, Mauck R, Gahan J, Hutchinson R, Torrealba J, Francis F, Roehrborn C, Strand D. Molecular pathogenesis of human prostate basal cell hyperplasia. Prostate. 2017 May; 77(13):1344–1355.

Costa DN, Chatzinoff Y, Passoni NM, Kapur P, Roehrborn CG, Xi Y, Rofsky NM, Torrealba J, Francis F, Futch C, Hagens P, Notgrass H, Otero-Muinelo S, Pedrosa I, Chopra R. Improved Magnetic Resonance Imaging-Pathology Correlation With Imaging-Derived, 3D-Printed, Patient-Specific Whole-Mount Molds of the Prostate. Invest Radiol. 2017 Sep; 52(9):507–513.

Zhou H, Hallac RR, Yuan Q, Ding Y, Zhang Z, Xie XJ, Francis F, Roehrborn CG, Sims RD, Costa DN, Raj GV, Mason RP. Incorporating Oxygen-Enhanced MRI into Multi-Parametric Assessment of Human Prostate Cancer. Diagnostics. 2017 Aug 24; 7(3). pii: E48.

Costa DN, Kay FU, Pedrosa I, Kolski L, Lotan Y, Roehrborn CG, Hornberger B, Xi Y, Francis F, Rofsky NM. An initial negative round of targeted biopsies in men with highly suspicious multiparametric magnetic resonance findings does not exclude clinically significant prostate cancer-preliminary experience. Urologic Oncology. April 2017, 35(4), pp149e.15–149e.21.

Costa DN, Yuan Q, Xi Y, Rofsky NM, Lenkinski RE, Lotan Y, Roehrborn C, Francis F, Travalini D, Pedrosa I. Comparison of prostate cancer detection at 3-T MRI with and without an endorectal coil: A prospective, paired-patient study. Urologic Oncology. 2016 June; 34(6): 255.e7–255.e13.

Passoni NM, Shariat S, Bagrodia A, Francis F, Rachakonda V, Xylinas E, Kapur P, Sagalowsky AI, Lotan Y. Concordance in Biomarker Status Between Bladder Tumors at Time of Transurethral Resection and subsequent Radical Cystectomy: Results of a 5-year Prospective Study. Bladder Cancer. 2016; Volume 2(1):91–99.

Costa D, Lotan Y, Rofsky NM, Roehrborn C, Liu A, Hornberger B, Xi Y, Francis F, Pedrosa I. Assessment of Prospectively Assigned Likert Scores for Targeted MR Imaging-Transrectal US Fusion Biopsies in Patients with Suspected Prostate Cancer. Journal of Urology. 2016; 195(1): 80–7.

Recavarren C, Labow DM, Liang J, Zhang L, Wong M, Zhu H, Wang J, Francis F, Xu R. Histologic characteristics of pancreatic intraepithelial neoplasia associated with different pancreatic lesions. Human Pathology. 2011; Volume 42(1):18–24.

Francis F, Roy S, Brady ST, Black MM. Transport of neurofilaments in growing axons requires microtubules but not actin filaments. Journal of Neuroscience Research. 2005 Volume 79 Issue 4: Pages 442–450.

He Y, Francis F, Myers KA, Yu W, Black MM, Baas PW. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. Journal of Cell Biology; 2005 Volume 168: Pages 697–703.


Francis FMD, PhD and Zhou M, MD, PhD, Pathology of Renal Cell Carcinoma. In: Renal Cancer: Contemporary Management, 2nd Ed. Springer, New York; 2020; Editors: Libertino, John; Gee, Jason.

Francis FMD, PhD and Zhou M, MD, PhD, Clinical Applications of Immunohistochemistry in Germ Cell Tumors in Men. In: Testicular Germ Cell Tumors, Methods and Protocols. Springer, New York; 2020; Editors: Bagrodia, Aditya; Amatruda, James.