Expert Pathologists

M.H. Saboorian, MD

Head of General Surgical Pathology and Cytology

Academic Appointments

2005–2006 Professor of Pathology, UT Southwestern Medical Center

1999–2005 Associate Professor and Director of Breast Pathology, UT Southwestern Medical Center

1993–1999 Assistant Professor of Pathology, UT Southwestern Medical Center

1992–1993 Pathology Faculty Associate, MD Anderson Cancer Center

Postdoctoral Training

1991–1992 Fellow in Surgical Pathology, MD Anderson Cancer Center

1987–1991 Resident in Pathology, University of Cincinnati


1984 MD, University of Hamburg


1992 Anatomic and Clinical Pathology (recertified 2008)

1993 Cytopathology

Professional Societies

American Society of Clinical Pathologists

President, Texas Society of Cytology

Select Publications

Meng S, Tripathy D, Shete S, Ashfaq R, Saboorian H, Haley B, Frenkel E, Euhus D, Leitch M, Osborne C, Clifford E, Perkins S, Beitsch P, Khan A, Morrison L, Herlyn D, Terstappen LW, Lane N, Wang J, Uhr J. uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues. Proc Natl Acad Sci USA. 2006 Nov 14; 103(46):17361–5.

Sharma S, Saboorian HM, Frawley WH, Frenkel EP, Haley BB, Ashfaq R. MIB1 labeling index as an indicator of chemoresponse in carcinoma of the breast. Appl Immunohistochem Mol Morphol. 2004 Dec; 12(4):290–5.

Roberts CA, Beitsch PD, Litz CE, Hilton DS, Ewing GE, Clifford E, Taylor W, Hapke MR, Babaian A, Khalid I, Hall JD, Lindberg G, Molberg K, Saboorian H. Interpretive disparity among pathologists in breast sentinel lymph node evaluation. Am J Surg. 2003 Oct; 186(4):324–9.

Sakaguchi M, Virmani A, Dudak MW, Peters GN, Leitch AM, Saboorian H, Gazdar AF, Euhus DM. Clinical relevance of reverse transcriptase-polymerase chain reaction for the detection of axillary lymph node metastases in breast cancer. Ann Surg Oncol. 2003 Mar; 10(2):117–25.

Fehm T, Morrison L, Saboorian H, Hynan L, Tucker T, Uhr J. Patterns of aneusomy for three chromosomes in individual cells from breast cancer tumors. Breast Cancer Res Treat. 2002 Oct; 75(3):227–39.

Euhus DM, Peters GN, Leitch AM, Saboorian H, Mathews D, Erdman W, Anglin B, Huth J. Validating the performance of the mammary sentinel lymph node team. J Surg Oncol. 2002 Apr; 79(4):209-15.

Wang S, Hossein Saboorian M, Frenkel EP, Haley BB, Siddiqui MT, Gokaslan S, Hynan L, Ashfaq R. Aneusomy 17 in breast cancer: its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status. Mod Pathol. 2002 Feb; 15(2):137–45.

Wang S, Saboorian MH, Frenkel EP, Haley BB, Siddiqui MT, Gokaslan S, Wians FH Jr, Hynan L, Ashfaq R. Assessment of HER-2/neu status in breast cancer. Automated Cellular Imaging System (ACIS)-assisted quantitation of immunohistochemical assay achieves high accuracy in comparison with fluorescence in situ hybridization assay as the standard. Am J Clin Pathol. 2001 Oct; 116(4):495–503.

Yashima K, Milchgrub S, Gollahon LS, Maitra A, Saboorian MH, Shay JW, Gazdar AF. Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma. Clin Cancer Res. 1998 Jan; 4(1):229–34.

Chinsoo Cho L, Spangkr A, Nguyen P, Leitch AM, Euhus D, Saboorian H. The role of cytokeratin immunohistochemical stain of axillary sentinel lymph nodes as a predictor of axillary lymph node dissection findings. Cancer Journal. 1996; 9(6), 514.

Saboorian MH, Kenny M, Ashfaq R, Albores-Saavedra J. Carcinosarcoma arising in eccrine spiradenoma of the breast. Report of a case and review of the literature. Arch Pathol Lab Med. 1996 May; 120(5):501–4.

Saboorian MH, Genta RM, Marcus P, Lindberg GM, Neumann WL. Inverse Association of Esophageal Eosinophilia and Barrett’s Esophagus. J Clin Gastroenterol 2012 Oct; 46(9):752–7.

Islam S, West AM, Saboorian MH, Ashfaq R. Reprocessing unsatisfactory ThinPrep Papanicolaou test specimens increases sample adequacy and detection of significant cervicovaginal lesions. Cancer. 2004 Apr 25; 102(2):67–73.

Roberts CA, Beitsch PD, Litz CE, Hilton DS, Ewing GE, Clifford E, Taylor W, Hapke MR, Babaian A, Khalid I, Hall JD, Lindberg G, Molberg K, Saboorian H. Interpretive disparity among pathologists in breastsentinel lymph node evaluation. Am J Surg, 186(4):324–9, 2003.

Siddiqui MT, Gokaslan ST, Saboorian MH, Carrick K, Ashfaq R. Comparison of ThinPrep and conventional smears in detecting carcinoma in bile duct brushings. Cancer, 99(4):205–10, 2003.

Rakheja D, Hoang MP, Myers LL, Saboorian MH. Pathologic quiz case: upper aerodigestive tract mass in a 90-year-old woman. Arch Pathol Lab Med, 127(6):E279–80, 2003.

Sarode VR, Werner C, Gander R, Foster B, Fulmer A, Saboorian MH, Ashfaq R. Reflex human papillomavirus DNA testing on residual liquid-based (TPPT) cervical samples: focus on age-stratified clinical performance. Cancer, 99(3):149–55, 2003.