Wei Tian, MD

2013-2014 Fellow, Genitourinary Pathology, Johns Hopkins Hospital

2012 Fellow, Surgical Pathology, Oregon Health & Science University

2010–2012 Resident, Anatomic and Clinical Pathology, Oregon Health & Science University

2008–2009 Resident, Anatomic and Clinical Pathology, Brown University

1998–2007 Postdoctoral Research Fellow, Research Associate, Division of Nephrology & Hypertension, Oregon

Health & Science University

1997–1998 Postdoctoral Research Fellow, Brigham and Women’s Hospital, Harvard Medical School

1992 MD, Norman Bethune University of Medical Sciences, Medicine in English, Changchun, Jilin, China

Anatomic Pathology, American Board of Pathology

Clinical Pathology, American Board of Pathology

United States & Canadian Academy of Pathology

College of American Pathologists

American Urological Association 

Genitourinary Pathology Society 

International Society of Urological Pathology

Tian W, Shore KT, Shah RB. Significant Reduction of Indeterminate (Atypical) Diagnosis after Implementation of The Paris System for Reporting Urinary Cytology: A Single Institutional Study of More Than 27,000 Cases. In prep.

Shah RB, Shore KT, Tian W. PTEN loss in prostatic adenocarcinoma correlates with specific adverse histologic features (intraductal carcinoma, cribriform Gleason pattern 4 and stromogenic carcinoma. Prostate. 2019 Aug; 79(11):1267–73.

Tian W, Dorn D, Wei S, Sanders RD, Matoso A, Shah RB, Gordetsky J. GATA3 expression in benign prostate glands with radiation atypia: a diagnostic pitfall. Histopathology. 2017 Jul;71(1):150–5.

Shah RB, Yoon J, Liu G, Tian W. Atypical Intraductal Proliferation and Intraductal Carcinoma of the Prostate on Core Needle Biopsy: A Comparative Clinicopathological and Molecular Study with a Proposal to Expand Morphological Spectrum of Intraductal Carcinoma. Histopathology. 2017  Nov;71(5):693–702.

Flamiatos JF, Beer TM, Graff JN, Eilers KM, Tian W, Sekhon HS, Garzotto M. Cyclooxygenase-2 (COX-2) inhibition for prostate cancer chemoprevention: double-blind randomised study of pre-prostatectomy celecoxib or placebo. BJU Int. 2017 May;119(5):709–16. 

Shah RB, Leandro G, Romerocases G, Bentley J, Yoon J, Mendrinos S, Tadros Y, Tian W, Lash R. Improvement in inter-observer reproducibility in resolving an “Atypical glands suspicious for prostate cancer” diagnosis in prostate biopsies using a novel “Diseased focused diagnostic review” quality process. Human Pathol, 2016 56: 155–62. (Featured as Top 10 (#3) Best articles of 2016 by Pathology Editor’s Choice by MDLinx Pathology)

Zhou M, Li J, Cheng L, Egevad L, Deng FM, Kunju LP, Magi-Galluzzi C, Melamed J, Mehra R, Mendrinos S, Osunkoya AO, Paner G, Shen SS, Tsuzuki T, Trpkov K, Tian W, Yang X, Shah RB. Diagnosis of “Poorly Formed Glands” Gleason Pattern 4 Prostatic Adenocarcinoma on Needle Biopsy: An Interobserver Reproducibility Study Among Urologic Pathologists With Recommendations. Am J Surg Pathol. 2015 Oct;39(10):1331–9

Shah RB, Li J, Cheng L, Egevad L, Deng FM, Fine SW, Kunju LP, Melamed J, Mehra R, Osunkoya AO, Paner GP, Shen SS, Tsuzuki T, Trpkov K, Tian W, Yang XJ, Zhou M. Diagnosis of Gleason pattern 5 prostate adenocarcinoma on core needle biopsy: an interobserver reproducibility study among urologic pathologists. Am J Surg Pathol. 2015 Sep;39(9):1242–9.

Tian W, Epstein JI. Invasive low-grade papillary urothelial carcinoma: an immunohistochemical study of 26 cases. Hum Pathol. 2015 Dec; 46(12):1836–41.

Tian W, Epstein JI, Netto G, etc. Utility of Uroplakin II expression as a Marker of Urothelial Carcinoma. Human Pathology. 2015 Jan;46(1):58–64.

Zhong M, Tian W, Zhuge J, Zheng X, Huang T, Cai D, Zhang D, Yang XJ, Argani P, Fallon JT, Epstein JI. Distinguishing Nested Variants of Urothelial Carcinoma From Benign Mimickers by TERT Promoter Mutation. Am J Surg Pathol. 2015 Jan;39(1):127–31.

Tian W, Latour M, Epstein JI. Endometrial Stromal Sarcoma Involving The Urinary Bladder: A Study of 6 Cases. Am J Surg Pathol 2014 Jul;38(7):982–9.

Cao WB, Tian W, Hong J, Li D, Tavares R, Noble L, Moss SF, Resnick MB. Expression of bile acid receptor TGR5 in gastric adenocarcinoma. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G322–7.

Friedlander J, Morgan T, Zhang Z, Tian W, Kehr E, Zigman A, Shackleton D, and, Stenzel P. Diagnosis of autoimmune pancreatitis vs neoplasms in children with pancreatic mass and biliary obstruction. Clinical Gastroenterology and Hepatology, 2012 Sep; 10(9):1051–5.

Tian W, Yakirevich E, Matoso A and Gnepp D. IgG4 positive plasma cells in sclerosing variant of mucoepidermoid carcinoma: a new and evolving concept. Am J of Surg Pathol. 2012 Jul; 36(7): 973–9.

Tian W, Fu Y, Garcia-Elias A, Fernandez-Fernandez J, Kramer P, Klein R ,  Hitzemann R, Orwoll E, Wilmot B, McWeeney S, Valverde M, Cohen DM. A loss-of-function non-synonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia. Proc Natl Acad Sci USA. 2009 Aug 18; 106(33):14034–9.

Fu Y, Tian W, Pratt EB, Dirling L, Shyng SL, Meshul CK, Cohen DM. Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion. PLoS One. 2009 May 25; 4(5): e5679.

Tian W, Fu Y, Wang DH, Cohen DM. Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant. Am J Physiol Renal Physiol. 2006 Jan; 290(1):F117–26.

Tian W, Salanova M, Xu H, Lindsley JN, Oyama TT, Anderson S, Bachmann S, Cohen DM. Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments. Am J Physiol Renal Physiol. 2004 Jul; 287(1): F17–24.

Xu H, Zhao H, Tian W, Yoshida K. Roullet JB, Cohen DM. Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. J Biol Chem. 2003 Mar 28; 278(13):11520–7.

Zhao H, Tian W, Xu H, Cohen DM. Urea signalling to immediate-early gene transcription in renal medullary cells requires transactivation of the epidermal growth factor receptor. Biochem J. 2003 Mar 1; 370(Pt 2):479–87.

Tian W, Cohen DM. Urea stress is more akin to EGF exposure than to hypertonic stress in renal medullary cells. Am J Physiol Renal Physiol. 2002 Sep; 283(3):F388–98.

Tian W, Bonkovsky HL, Shibahara S, Cohen DM. Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells. Am J Physiol Renal Physiol. 2001 Nov; 281 (5):F983–91.

Tian W, Cohen DM. Signaling and gene regulation by urea in cells of the mammalian kidney medulla. Comp Biochem Physiol A Mol Integr Physiol. 2001 Oct; 130(3):429–36. Review.