H. pylori infection is declining in the industrialized world and emerging economies. Simultaneously, as the world population moves to a […]
Abstract Category: Abstracts & Presentations
Correlation of P16 Expression and Clinicopathologic Outcome of Anal Squamous Cell Carcinoma
Anal squamous cell carcinoma (ASCC) is uncommon, and accounts for 4% of carcinomas involving the gastrointestinal tract. The pathogenesis of […]
Submucosal Lipoma and Sessile Serrated Adenoma/Polyp, More Than Just a Coincidence?
In our practice we noticed that sessile serrated adenomas/polyps (SSA/P) were frequently associated with submucosal lipomas (SL). While this finding […]
Isolated Eosinophilic Colitis: A Challenging Diagnosis in Search of Criteria
Eosinophils infiltrate the colonic mucosa in response to tissue-invading parasites, as part of eosinophilic gastroenteritis (EoG), or as an isolated […]
Heterogeneity of PTEN and ERG Biomarkers Expression in Prostate Cancer Needle Biopsies with More Than One Core Positive: Implications for Biomarkers Sampling Strategy
Both PTEN and ERG biomarkers demonstrate significant inter- and intra-tumor core staining heterogeneity, suggesting that sampling may affect biomarkers interpretation. […]
Helicobacter-negative Chronic Active Gastritis is an Independent Nosologic Entity, Not Merely Missed Helicobacter Infection: A Nationwide Study of 600,000 Patients
Helicobacter-negative chronic active gastritis is a histopathologic entity characterized by diffuse chronic active inflammation in a pattern typically encountered in […]
Esophageal Eosinophilia and Gastric Mucosal Pathology: Is There a Link?
We have previously reported, and others have confirmed, an inverse relationship between eosinophilic esophagitis and Helicobacter pylori gastritis. Other conditions […]
Anal Canal Syphilis: A Challenging Diagnosis for the Gastrointestinal Pathologist
The rates of primary and secondary syphilis have been increasing in the United States since 2001, following a historic low […]
Eosinophilic Esophagitis is Associated with an Increased Prevalence of Inflammatory Bowel Disease
Eosinophilic esophagitis (EoE) is an increasingly prevalent chronic disease thought to arise from an allergy/immune-mediated process. Reports of patients with […]
Unexpected Candidiasis in the Endoscopically Normal Esophagus
We identified several cases in which a histopathologic diagnosis of Candida esophagitis was made in a patient with no known […]
Intestinal Spirochetosis is Associated with Diarrhea, Weight Loss and Abdominal Pain: A Study of 447 Patients and 1.2 Million Controls
Intestinal spirochetosis is a condition in which the colonic mucosa is colonized by anaerobic spirochetes, either Brachyspira aalborgi or Brachyspira […]
Low Prevalence of Colon Polyps in Patients with Diarrhea and Microscopic Colitis
Microscopic colitis (MC) is a condition that includes a spectrum of histological abnormalities of the colonic mucosa, ranging from an […]
Gastric Pathology in HIV-Infected Patients
Thirty years after its discovery, Helicobacter pylori remains the world’s most common infectious agent, with an estimated prevalence ranging from […]
Proton Pump Inhibitor Use in Patients with Helicobacter Gastritis is Associated with a High Prevalence of Corpus-Predominant Gastritis and Intestinal Metaplasia
European studies have shown that long-term proton-pump inhibitor (PPI) therapy in patients with GERD and antrum-predominant (AP) gastritis may induce […]
Recognition of the null staining pattern increases the utility of p53 IHC in Barrett’s esophagus
Mutation and/or deletion of p53, a cell cycle regulatory gene, is a promising biomarker for predicting the risk of neoplastic […]
