Categorized: Abstracts & Presentations, Urology

Anal Canal Syphilis: A Challenging Diagnosis for the Gastrointestinal Pathologist

The rates of primary and secondary syphilis have been increasing in the United States since 2001, following a historic low in 2000.

The manifestations of syphilis as a genital disease are well described; however, its presentation as primary anal canal disease remains relatively unexplored.

Although the demonstration of serum antibodies has traditionally remained the mainstay for diagnosis of syphilis in the past, pathologists occasionally encounter an anal canal biopsy in which syphilis may be a consideration in the histologic differential diagnosis.

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