Scientific Publications
Recent publications in Urology
At Inform Diagnostics, our uropathologists see more cases per year than the average uropathologist. In addition, we encourage ongoing research and education and are proud of the peer-reviewed research our uropathologists have published. Read their latest research below, including pioneering work in areas such as atypical intraductal proliferation and intraductal carcinoma of prostate (IDC-P).
Assessment of prospectively assigned Likert scores for targeted MR imaging-transrectal US fusion biopsies in patients with suspected prostate cancer
Published in Journal of Urology, 2016. Authors: Costa D, Lotan Y, Rofsky NM, Roehrborn C, Liu A, Hornberger B, Xi Y, Francis F, and Pedrosa I. For a copy, please contact Inform…
An initial negative round of targeted biopsies in men with highly suspicious multiparametric magnetic resonance findings does not exclude clinically significant prostate cancer-preliminary experience
Published in Urologic Oncology, April 2017. Authors: Costa DN, Kay FU, Pedrosa I, Kolski L, Lotan Y, Roehrborn CG, Hornberger B, Xi Y, Francis F, and Rofsky NM. For a copy,…
Optimal sampling scheme in men with abnormal multiparametric MRI undergoing MRI-TRUS fusion prostate biopsy
Published in Urologic Oncology, January 2019. Authors: Freifeld Y, Xi Y, Passoni N, Woldu S, Hornberger B, Goldberg K, Bagrodia A, Raj G, Margulis V, Cadeddu JA, Lotan Y, Francis F,…
Molecular Subtyping of Clinically Localized Urothelial Carcinoma Reveals Lower Rates of Pathological Upstaging at Radical Cystectomy Among Luminal Tumors
Published in European Urology, August 2019. Authors: Lotan Y, Boorjian SA, Zhang J, Bivalacqua TJ, Porten SP, Wheeler T, Lerner SP, Hutchinson R, Francis F, Davicioni E, Svatek RS, Chen CL,…
Utility of PTEN and ERG Immunostaining for Distinguishing High-grade PIN from Intraductal Carcinoma of the Prostate on Needle Biopsy
Published in The American Journal of Surgical Pathology, 2015. Authors: Morais CL, Han JS, Gordetsky J, Nagar MS, Anderson AE, Lee S, Hicks JL, Zhou M, Magi-Galluzzi C, Shah RB, Epstein…
Heterogeneity of PTEN and ERG Expression in Prostate Cancer on Core Needle Biopsies: Implications for Cancer Risk Stratification and Biomarker Sampling
Published in Human Pathology, 2015. Authors: Shah RB, Bentley J, Jeffery Z and DeMarzo AM. For a copy, please contact Inform Diagnostics.
Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent
Published in The American Journal of Clinical and Experimental Urology, 2015. Authors: Begley LA, Kasina S, Shah RB, and Macoska JA. For a copy, please contact Inform Diagnostics.
ERG overexpression and multifocality predict prostate cancer in subsequent biopsy for patients with high-grade prostatic intraepithelial neoplasia
Published in Urologic Oncology, 2015. Authors: Shah RB, Li J, Dhanani N, and Mendrinos S. For a copy, please contact Inform Diagnostics.
Diagnosis of Gleason pattern 5 prostate adenocarcinoma on core needle biopsy: an interobserver reproducibility study among urologic pathologists
Published in The American Journal of Surgical Pathology, September 2015. Authors: Shah RB, Li J, Cheng L, Egevad L, Deng FM, Fine SW, Kunju LP, Melamed J, Mehra R, Osunkoya AO, Paner…
Diagnosis of “poorly formed glands” Gleason pattern 4 prostatic adenocarcinoma on needle biopsy: an interobserver reproducibility study among urologic pathologists with recommendations
Published in The American Journal of Surgical Pathology, October 2015. Authors: Zhou M, Li J, Cheng L, Egevad L, Deng FM, Kunju LP, Magi-Galluzzi C, Melamed J, Mehra R, Mendrinos S, Osunkoya…
Improvement in inter-observer reproducibility in resolving an “Atypical glands suspicious for prostate cancer” diagnosis in prostate biopsies using a novel “Diseased focused diagnostic review” quality process
Published in Human Pathology, 2016. Authors: Shah RB, Leandro G, Romerocases G, Bentley J, Yoon J, Mendrinos S, Tadros Y, Tian W, and Lash R. For a copy, please contact Inform Diagnostics.
Atypical intraductal proliferation and intraductal carcinoma of the prostate on core needle biopsy: a comparative clinicopathological and molecular study with a proposal to expand morphological spectrum of intraductal carcinoma
Published in Histopathology, November 2017. Authors: Shah RB, Yoon J, Liu G, and Tian W. For a copy, please contact Inform Diagnostics.
GATA3 expression in benign prostate glands with radiation atypia: a diagnostic pitfall
Published in Histopathology, July 2017. Authors: Tian W, Dorn D, Wei S, Sanders RD, Matoso A, Shah RB, and Gordetsky J. For a copy, please contact Inform Diagnostics.
PTEN loss in prostatic adenocarcinoma correlates with specific adverse histologic features (intraductal carcinoma, cribriform Gleason pattern 4 and stromogenic carcinoma
Published in Prostate, August 2019. Authors: Shah RB, Shore KT, and Tian W. For a copy, please contact Inform Diagnostics.
Urine cytology diagnostic patterns before and after implementing the paris system for reporting urine cytology: a large single institutional study of over 27,000 cases
In prep. Authors: Tian W, Shore KT, and Shah RB. For a copy, please contact Inform Diagnostics.
Incidence and clinicopathological characteristics of Gleason pattern 5 prostate cancer in contemporary needle biopsies series: a prospective study
Poster presentation given to the United States and Canadian Academy of Pathology’s 2014 Annual Meeting in San Diego, CA. For a copy, please contact Inform Diagnostics.
Antibody based detection of ERG gene fusions in prostate cancer: An Immunohistochemical study comparing C- and N-terminus ERG antibodies
Given to the United States and Canadian Academy of Pathology’s 2012 Annual Meeting in Vancouver, BC, Canada. For a copy, please contact Inform Diagnostics.
How often does ERG contribute to resolving an “Atypical Glands Suspicious for Cancer” diagnosis in prostate biopsies beyond that provided by basal cell and Alpha-Methylacyl-CoA-Racemase (AMACR) markers?
Presentation given to the United States and Canadian Academy of Pathology’s 2012 Annual Meeting in Vancouver, BC, Canada. For a copy, please contact Inform Diagnostics.
Heterogeneity of PTEN and ERG biomarkers expression in prostate cancer needle biopsies with more than one core positive: Implications for biomarkers sampling strategy
Poster presentation given to the United States and Canadian Academy of Pathology’s 2014 Annual Meeting in San Diego, CA. For a copy, please contact Inform Diagnostics.
Diagnosis of “poorly formed glands” Gleason pattern 4 prostatic adenocarcinoma on needle biopsy: an interobserver reproducibility study among urologic pathologists with recommendations
Zhou M, Tian W, Yang X, Shah RB, and others Poster presentation given to the United States and Canadian Academy of Pathology’s 2015 Annual Meeting in Boston, MA. For a copy, please…
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