Categorized: Gastroenterology, Peer-Reviewed
Inverse Association of Esophageal Eosinophilia With Helicobacter pylori Based on Analysis of a US Pathology Database
Evan S. Dellon, Anne F. Peery, Nicholas J. Shaheen, Douglas R. Morgan, Jennifer M. Hurrell, Richard H. Lash, Robert M. Genta
Published in Gastroenterology, 2011.
Eosinophilic esophagitis (EoE) is of increasing prevalence and believed to result from allergic processes. Helicobacter pylori has been inversely associated with allergic diseases, but there is no known relationship between H pylori, EoE, and esophageal eosinophilia. We investigated the association between esophageal eosinophilia and H pylori infection.
We performed a crosssectional study of data, collected from a US pathology database, on 165,017 patients in the United States who underwent esophageal and gastric biopsies from 2008 through 2010. Patients with and without H pylori on gastric biopsy were compared, and odds of esophageal eosinophilia were