Scientific Publications

Categorized: Urology

Predictive Value of ERG Oncoprotein Expression and Pathologic Parameters In the Stratification of Prostate Cancer Risk Associated With High Grade Prostatic Intraepithelial Neoplasia (HGPIN) Diagnosis In Prostate Needle Biopsy

This research was presented at the AUA annual conference in May 2015, in New Orleans.

High-grade prostatic intraepithelial neoplasia (HGPIN) is a putative neoplastic precursor lesion of prostate cancer (PCa). Historically, HGPIN in needle biopsy has been associated with high predictability of finding a cancer in repeat biopsy (~40%); however, the diagnosis rates of PCa after an initial diagnosis of HGPIN have significantly decreased in recent years (~25%) as utilization of extended biopsy templates have reduced the number of cancers missed on initial biopsy.

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