Categorized: Gastroenterology

Prevalence and Clinical Correlations of Reactive Gastropathy in Children and Younger Adults

SD Melton and RM Genta, Inform Diagnostics Research Institute, Irving, TX; Department of Pathology, Dallas VA Medical Center – UT Southwestern Medical Center, Dallas, Texas

Reactive (or chemical) gastropathy (RG), an entity characterized by foveolar hyperplasia, projections of smooth muscle fibers into the lamina propria, edema, and hyperemia. RG is most commonly seen in older adults and is believed to be associated with either medications (mostly NSAIDs) or bile reflux. However, RG is detected with increasing frequency in younger adults and even children, despite the apparent lack of obvious risk factors.

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