Categorized: Abstracts & Presentations, Gastroenterology

Subepithelial Fibrosis is a Distinctive Characteristic of Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic, allergy-related disease in which prolonged eosinophil-predominant inflammation can cause tissue remodeling. The remodeling results in serious complications including esophageal rings, strictures, and mucosal fragility, which can cause dysphagia, food impactions, and painful mucosal tears. A feature of the remodeling is the pattern of dense, subepithelial fibrosis in the lamina propria, and it is unclear whether this subepithelial fibrosis is unique to EoE.

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