Scientific Publications
Recent publications in Gastroenterology
Inform Diagnostics fosters an academic environment where ongoing research and education are encouraged. Read the latest abstracts, articles, and publications from the GI pathologists at Inform Diagnostics.
The Inlet Patch Revisited: A Clinicopathologic Study of 569 Patients with Heterotopic Gastric Mucosa in the Proximal Esophagus
Giovanni M. Luján, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Heterotopic gastric mucosa in the proximal esophagus also reported as inlet patch is considered a congenital anomaly of…
Rare Presentation of Gastrointestinal Mantle Cell Lymphoma
Danielle Morris, Nicolas Sun, Shawn Kinsey, University of Texas Southwestern Medical Center Department of Pathology, Jackson Gastro Center LLC, Jackson, MI, Inform Diagnostics Research Institute, Irving, TX Colorectal lymphomas are…
What are Immunohistochemical Stains?
When reading a surgical pathology report, you may have wondered exactly what are immunohistochemical (IHC) stains and what are their purpose? Although the basic principle of IHC was described in…
Proton Pump Inhibitors and Lymphocytic Esophagitis : A Novel Association?
Salima Haque, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Lymphocytic esophagitis was first described by Rubio et al. as an entity in 2006; however, in 2008 Purdy et…
Laboratory Screening of Colorectal Cancer Patients in Routine Practice Identifies Probable Lynch Syndrome Patients at a High Frequency, Even Among Older Patients
Mark Redston and Richard Lash, Inform Diagnostics Research Institute, Inform Diagnostics, Newton, MA and Irving, TX Lynch Syndrome (LS) is a clinically important colorectal and extracolonic cancer predisposition syndrome that…
Malakoplakia
Guy M. Lindberg, Robert M. Genta, M.H. Saboorian, Inform Diagnostics Research Institute, Irving, TX Malakoplakia (MP) is a rare granulomatous condition thought to result from the insufficient killing of bacteria…
Microscopic Colitis-Like Histologic Changes in Idiopathic Inflammatory Bowel Disease Patients: A Clinicopathologic Study Utilizing a National Pathology Database
Jonathan N. Glickman, Anuradha Singhal, Inform Diagnostics Research Institute, Irving, TX Collagenous colitis (CC) and lymphocytic colitis (LC), collectively termed microscopic colitis (MC), are chronic watery diarrheal disorders that most…
Influence of Sampling Strategy and Utility of Rectal Biopsy in the Diagnosis of Collagenous and Lymphocytic Colitis.
Jonathan N. Glickman, Inform Diagnostics Research Institute, Irving, TX Collagenous colitis (CC) and lymphocytic colitis (LC) are chronic watery diarrheal disorders that most commonly affect middle aged to elderly adults.…
Primary Myeloid Sarcoma of the Colon in a 71 Year Old Male Presenting as a Nodule During Screening Colonoscopy
Jeremy S. Ditelberg MD, Ahmed Bedeir MD, Parag Patel DO, Inform Diagnostics Research Institute, Newton, MA Myeloid sarcoma (MS) is a solid tumor composed of myeloblasts occurring outside of the…
Prevalence and Clinical Correlations of Reactive Gastropathy in Children and Younger Adults
SD Melton and RM Genta, Inform Diagnostics Research Institute, Irving, TX; Department of Pathology, Dallas VA Medical Center – UT Southwestern Medical Center, Dallas, Texas Reactive (or chemical) gastropathy (RG),…
Incidental Strongyloidiasis in Colonic Biopsy Specimens
M.H. Saboorian, Guy M. Lindberg, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Strongyloides stercoralis, a worldwide parasitic nematode, can persist indefinitely within a host, usually asymptomatic, through a…
A Descriptive Analysis of Colorectal Carcinoma in Patients with Ulcerative Colitis Seen Over a Three Year Period
Patients with longstanding and extensive ulcerative colitis (UC) are at increased risk for developing colorectal carcinoma (CRC). Recent epidemiologic studies have suggested an overall decrease in the incidence of CRC…
Prevalence of Rectal Carcinoid Tumors among Outpatient Colonoscopy Patients and the Utility of Immunohistochemistry for Definitive Diagnosis
Rectal carcinoid tumors are rare (0.05% in the general population, SEER data) and are usually discovered incidentally in routine colonoscopy biopsies. Although immunohistochemistry with neuroendocrine markers synaptophysin and/or chromogranin is…
Size-specific prevalence of colorectal adenomas with high grade dysplasia: results from a nationally representative sample with implications for CT colonography practice
The aim of this cross-sectional study was to estimate size-specific prevalence of high grade dysplasia among adenomas identified from a nationally representative sample of colorectal specimens. To read the rest…
High Yield of Lynch Syndrome Screening in Pre-Cancerous Colorectal Polyps: A Study of 898 Patients
Lynch Syndrome research presented at DDW 2011 by Mark Redston, MD and Richard Lash, MD, found that the prevalence of LS among patients with newly diagnosed HGD adenomas in the…
Gastric Cardiac Polyps: A Clinicopathologic Study of 330 Cases
Published by American Journal of Surgical Pathology, December 2010 Shelby D. Melton, MD, and Robert M. Genta, MD Clinically apparent cytomegalovirus (CMV) colitis in adults is most frequently found in…
Eosinophilic Gastritis: A Histopathologic Diagnosis in Search of Clinical Correlates
Published in Modern Pathology, December 17, 2010 Thida Lwin, MD, Shelby D. Melton, MD, and Robert M. Genta, MD Eosinophilic gastritis remains a poorly characterized condition that pathologists may consider…
