Scientific Publications
Recent publications, abstracts, and presentations
Our fellowship-trained pathologists actively participate in research initiatives and present their work at internationally attended conferences. See their latest work in their areas of subspecialty expertise.
Primary Myeloid Sarcoma of the Colon in a 71 Year Old Male Presenting as a Nodule During Screening Colonoscopy
Jeremy S. Ditelberg MD, Ahmed Bedeir MD, Parag Patel DO, Inform Diagnostics Research Institute, Newton, MA Myeloid sarcoma (MS) is a solid tumor composed of myeloblasts occurring outside of the…
Prevalence and Clinical Correlations of Reactive Gastropathy in Children and Younger Adults
SD Melton and RM Genta, Inform Diagnostics Research Institute, Irving, TX; Department of Pathology, Dallas VA Medical Center – UT Southwestern Medical Center, Dallas, Texas Reactive (or chemical) gastropathy (RG),…
Incidental Strongyloidiasis in Colonic Biopsy Specimens
M.H. Saboorian, Guy M. Lindberg, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Strongyloides stercoralis, a worldwide parasitic nematode, can persist indefinitely within a host, usually asymptomatic, through a…
A Descriptive Analysis of Colorectal Carcinoma in Patients with Ulcerative Colitis Seen Over a Three Year Period
Patients with longstanding and extensive ulcerative colitis (UC) are at increased risk for developing colorectal carcinoma (CRC). Recent epidemiologic studies have suggested an overall decrease in the incidence of CRC…
Prevalence of Rectal Carcinoid Tumors among Outpatient Colonoscopy Patients and the Utility of Immunohistochemistry for Definitive Diagnosis
Rectal carcinoid tumors are rare (0.05% in the general population, SEER data) and are usually discovered incidentally in routine colonoscopy biopsies. Although immunohistochemistry with neuroendocrine markers synaptophysin and/or chromogranin is…
Size-specific prevalence of colorectal adenomas with high grade dysplasia: results from a nationally representative sample with implications for CT colonography practice
The aim of this cross-sectional study was to estimate size-specific prevalence of high grade dysplasia among adenomas identified from a nationally representative sample of colorectal specimens. To read the rest…
High Yield of Lynch Syndrome Screening in Pre-Cancerous Colorectal Polyps: A Study of 898 Patients
Lynch Syndrome research presented at DDW 2011 by Mark Redston, MD and Richard Lash, MD, found that the prevalence of LS among patients with newly diagnosed HGD adenomas in the…
Gastric Cardiac Polyps: A Clinicopathologic Study of 330 Cases
Published by American Journal of Surgical Pathology, December 2010 Shelby D. Melton, MD, and Robert M. Genta, MD Clinically apparent cytomegalovirus (CMV) colitis in adults is most frequently found in…
Eosinophilic Gastritis: A Histopathologic Diagnosis in Search of Clinical Correlates
Published in Modern Pathology, December 17, 2010 Thida Lwin, MD, Shelby D. Melton, MD, and Robert M. Genta, MD Eosinophilic gastritis remains a poorly characterized condition that pathologists may consider…
Paroxysmal Nocturnal Hemoglobinuria (PNH): A Life Threatening Disease Caused by Unregulated Complement Activation
In clinical terms, paroxysmal nocturnal hemoglobinuria (PNH) is synonymous with glycosylphosphatidylinositol (GPI) deficiency, and is an acquired clonal disorder associated with somatic mutations of the X-linked PIGA gene in hematopoietic…
The Role of Flow Cytometry in the Diagnosis of PNH
Screening and diagnosis of patients with PNH has improved with the development of flow cytometry.1 Immunophenotypic analysis of GPI-linked antigen expression on red cells and peripheral blood granulocytes by flow…
Plasma Cell Enrichment: Increasing the Detection Rate of Plasma Cell Disorders
Plasma cell enrichment techniques concentrate the overall population of plasma cells, thereby increasing the detection and frequency of abnormalities. Cytogenetic analysis of plasma cell disorders (PCD) is difficult due to…
