Scientific Publications
Recent publications, abstracts, and presentations
Our fellowship-trained pathologists actively participate in research initiatives and present their work at internationally attended conferences. See their latest work in their areas of subspecialty expertise.
Reactive Gastropathy is Associated with Inflammatory Conditions Throughout the Gastrointestinal Tract
Reactive gastropathy is a histopathologic term widely understood by gastroenterologists as an indication of gastric damage associated with either bile reflux or chronic NSAID use. The epidemiology of reactive gastropathy…
Immunohistochemical Staining for p53 Protein in Barrett’s Esophagus
An Emerging Ancillary Technique in Risk Stratification The diagnosis of dysplasia in the setting of Barrett’s esophagus is one of the most challenging areas of GI pathology and is associated…
American College of Gastroenterology: 2011 Annual Scientific Meeting
Another Major Presence for Inform Diagnostics Washington, D.C. – For the past four years, the conspicuous presence of researchers from Inform Diagnostics has become a tradition at the annual meeting…
What to do about: Low level monoclonal B-lymphocyte populations
In recent years, flow cytometric analysis of the blood and bone marrow has become a standard of practice for the evaluation of patients having hematologic abnormalities, primarily for the identification…
Getting to the point: Somatic point mutations influence the clinical features and survival in myelodysplastic syndromes
According to the National Institutes of Health, the frequency and incidence of myelodysplastic syndromes (MDS) is increasing in the US population and is influenced by factors such as advancing age,…
Barrett’s Metaplasia and Colonic Neoplasms Coincide in Identical Patients
More than 25 years ago, Sontag et al first reported an increased prevalence of colonic neoplasms in patients with Barrett’s esophagus. Many subsequent articles have been published, trying to confirm…
Lymphocytic Esophagitis: Shedding Fresh Light on a Mysterious Histopathologic Pattern
You may have received pathology reports with a diagnosis of “lymphocytic esophagitis pattern of injury” and asked youself two perfectly reasonable questions: 1. “Well, what does that mean?” 2. “Is…
CMV Colitis in Patients Undergoing Colonoscopy in Community-Based Endoscopy Centers
Reenu K. Malhotra, Anuradha Singhal, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Clinically apparent cytomegalovirus (CMV) colitis in adults is most frequently found in immunosuppressed patients, although sporadic…
Collagenous Colitis: A Clinical and Demographic Review of 2,368 Cases
Jeremy S. Ditelberg MD, Inform Diagnostics Research Institute, Newton, MA High-grade dysplasia (HGD) in colorectal adenomas is relevant for follow-up and management of patients with polyps. While some authors advocate…
Miraca Life Sciences Highlights at DDW 2011
At DDW this past May, Inform Diagnostics pathologists once again had a significant presence with two abstracts presented as oral platform presentations and six posters. Below are the two platform…
High-Grade Dysplasia in Colonic Adenomas Among 600,000 Colonoscopy Patients
M.H. Saboorian, R.H. Lash, Inform Diagnostics Research Institute, Irving, TX High-grade dysplasia (HGD) in colorectal adenomas is relevant for follow-up and management of patients with polyps. While some authors advocate…
Hyperplastic Polyp of the Colon: Age and Gender Distribution of 65,453 Cases
Jeremy S. Ditelberg MD, Inform Diagnostics Research Institute, Newton, MA The hyperplastic polyp (HP) is the most common polyp of the colon. This study examined 65,453 cases of HP in…
The Inlet Patch Revisited: A Clinicopathologic Study of 569 Patients with Heterotopic Gastric Mucosa in the Proximal Esophagus
Giovanni M. Luján, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Heterotopic gastric mucosa in the proximal esophagus also reported as inlet patch is considered a congenital anomaly of…
Rare Presentation of Gastrointestinal Mantle Cell Lymphoma
Danielle Morris, Nicolas Sun, Shawn Kinsey, University of Texas Southwestern Medical Center Department of Pathology, Jackson Gastro Center LLC, Jackson, MI, Inform Diagnostics Research Institute, Irving, TX Colorectal lymphomas are…
What are Immunohistochemical Stains?
When reading a surgical pathology report, you may have wondered exactly what are immunohistochemical (IHC) stains and what are their purpose? Although the basic principle of IHC was described in…
Proton Pump Inhibitors and Lymphocytic Esophagitis : A Novel Association?
Salima Haque, Robert M. Genta, Inform Diagnostics Research Institute, Irving, TX Lymphocytic esophagitis was first described by Rubio et al. as an entity in 2006; however, in 2008 Purdy et…
Laboratory Screening of Colorectal Cancer Patients in Routine Practice Identifies Probable Lynch Syndrome Patients at a High Frequency, Even Among Older Patients
Mark Redston and Richard Lash, Inform Diagnostics Research Institute, Inform Diagnostics, Newton, MA and Irving, TX Lynch Syndrome (LS) is a clinically important colorectal and extracolonic cancer predisposition syndrome that…
Malakoplakia
Guy M. Lindberg, Robert M. Genta, M.H. Saboorian, Inform Diagnostics Research Institute, Irving, TX Malakoplakia (MP) is a rare granulomatous condition thought to result from the insufficient killing of bacteria…
Microscopic Colitis-Like Histologic Changes in Idiopathic Inflammatory Bowel Disease Patients: A Clinicopathologic Study Utilizing a National Pathology Database
Jonathan N. Glickman, Anuradha Singhal, Inform Diagnostics Research Institute, Irving, TX Collagenous colitis (CC) and lymphocytic colitis (LC), collectively termed microscopic colitis (MC), are chronic watery diarrheal disorders that most…
Influence of Sampling Strategy and Utility of Rectal Biopsy in the Diagnosis of Collagenous and Lymphocytic Colitis.
Jonathan N. Glickman, Inform Diagnostics Research Institute, Irving, TX Collagenous colitis (CC) and lymphocytic colitis (LC) are chronic watery diarrheal disorders that most commonly affect middle aged to elderly adults.…
